As AI, the cloud, cybersecurity, and critical infrastructure reshape information systems, one question takes center stage: How is the role of humans evolving in environments that are increasingly automated, distributed, and under pressure? This roundtable will bring together diverse perspectives to explore the new dynamics of tomorrow’s information systems: who builds them, who governs them, who assumes the risks, and who actually reaps their value. Balancing operational constraints, cost control, resilience, security, sovereignty, and user experience, organizations must rethink how they manage information systems that have become more strategic, more complex, and more critical.